The Soulmate Equation

THEY FOLLOWED HIM through a set of sterile double doors and down a long hall, with offices coming off the right side every few yards. Each door had a hammered stainless steel placard and a name: Lisa Addams. Sanjeev Jariwala. David Morris. River Peña. Tiffany Fujita. Brandon Butkis.

Jess glanced over to Fizzy, who, predictably, was already on it: “Butt kiss,” she whispered, delighted.

Through one open office door, Jess saw a broad window displaying a view of the La Jolla shoreline. Less than a mile away, gulls swooped down over white-capped water, and waves crashed violently against rocky cliffs. It was spectacular.

The annual lease on this property had to be at least a kidney and a half.

The trio tromped along in silence, reaching a set of elevators. River pushed the Up button with a long index finger, and then stared wordlessly ahead.

The silence grew heavy. “How long have you worked here?” Jess asked.

“Since it was founded.”

Helpful. She tried again. “How many employees are there?”

“About a dozen.”

“It’s a shame you’re not in marketing,” Jess said with a smile. “Such charm.”

River turned to look at her, and his expression sent a cold wash of sensation down her arms. “Yes, well. Luckily my talents lie elsewhere.” His gaze lingered on hers for just a beat too long, and the sensation turned into warm static just as the elevator doors opened.

Fizzy elbowed her sharply in the ribs. Sexy things, she was clearly thinking.

Assassin things, Jess mentally replied.

For all of the promises of exploiting this great research opportunity, Fizzy was uncharacteristically quiet; maybe she was also cowed by River’s rigid presence. It meant the rest of the slow elevator ride was as wordless as the bleak center of Siberia. When they stepped out, Jess watched her best friend begin scribbling note after note about—she presumed—the building; the handful of buttoned-up scientists they passed in the second hallway; River’s composed pace, perfect posture, and visibly muscular thighs. Meanwhile, Jess grew increasingly self-conscious about the obnoxious squeak of her sneakers on the linoleum and the relative dumpiness of her outfit. Fizzy was dressed like she usually was—an adorable polka dot silk blouse and pencil trousers—and River was dressed as he usually was—a glossy magazine version of business casual. It hadn’t occurred to Jess that morning as she’d hurriedly pulled on a threadbare UCLA sweatshirt, some old Levi’s, and a pair of scuffed Vans that she would later be strolling down a hallway in the most well-heeled part of biotech La Jolla.

At the end of the hall was an open door leading into a conference room. River paused and gestured for them to walk in ahead of him.

“Have a seat in here,” he said. “Lisa will join you momentarily.”

Fizzy glanced to Jess and then back to River. “Who’s Lisa?”

“She’s the head of customer relations and the lead on our app development. She’ll explain the technology and the matching process.”

Frankly this whole thing had become a boatload of confusing secrecy. “You’re not staying?” Jess asked.

He looked affronted, like she’d suggested he was the company water boy. “No.” With a vague smile, he turned and continued down the hallway. Ass.

Only a couple of minutes later, a brunette walked in. She had the sun-kissed, faux-no-makeup, beachy-waved look of perpetually active Southern Californians who could throw on a shapeless muumuu and look stylish.

“Hey!” She strode forward, reaching to shake their hands. “I’m Lisa Addams. Head of customer relations for GeneticAlly. I’m so glad you came in! I haven’t given this presentation to such a small group yet, this’ll be a blast. Are you two ready?”

Fizzy nodded enthusiastically, but Jess was starting to feel a bit like she’d been dropped into a world where she was the only one not in on an important secret. “Would you mind showing me to the restroom before we start?” she asked, wincing lightly. “Coffee.”

With another smile, Lisa gave Jess directions that seemed simple enough. Jess passed a stretch of large doorways with a distinct laboratory vibe. One was labeled SAMPLE PREP. The next was DNA SEQUENCERS, followed by ANALYSIS 1, ANALYSIS 2, and SERVERS. Finally: an alcove with restrooms.

Even the toilets were futuristic. Jess was honestly not sure how to feel about a public bidet, but there were so many buttons on the thing—and hey, warm water—she decided to roll with it. A check of her reflection while she washed her hands informed her that she hadn’t put makeup on that morning and looked haggard and frazzled, even in the dim yet flattering light. Great.

On the way back, her attention was snagged by an open door. It had been forever since she’d been in a real scientific setting, and nostalgia pulsed in the back of her mind. Peeking into the room labeled SAMPLE PREP, Jess saw a long stretch of lab benches and an assortment of machines with keypads and flashing full-color digital displays like something out of a movie.

And then she heard River’s quiet, deep voice: “Isn’t there another 10X bottle of extraction buffer?”

“We have some on order,” another man replied. “I think I have enough to finish this set.”

“Good.”

“Did I hear you had two people come in for a demo?”

“Yes,” River said. “Two women. One of them is apparently an author with a large online presence.”

There was a pause that Jess assumed held some wordless communication.

“I don’t know, man,” River said. “I was just trying to get my coffee, so I suggested they come in so Lisa could handle it.”

Well.

“Got it,” the other voice said. “If they send in kits, I’ll run them in quadruplicate with some reference sequences.”

“There may be times soon after the rollout that we only have a handful of samples at a time, so this’ll be a good trial for that.”

“True.”

She was just about to turn and walk back to the conference room when she heard River say with a laugh, “—an opportunity to prove that there’s someone out there for everyone.”

The other man asked, “Ugly?”

“No, not ugly.” Jess immediately decided to receive this as River’s version of a compliment, until he added: “Entirely average.”

She reared back, palm to chest in genuine offense, and startled when a voice came from behind her. “Did you want a lab tour after your meeting with Lisa?”

The man behind her held his hands up as Jess wheeled on him like she might throw a punch. He was tall and thin and looked like every actor in every movie playing a scientist: Caucasian, glasses, needed a haircut. He was Jeff Goldblum, if Jeff Goldblum were also Benedict Cumberbatch.

She wasn’t sure whether he was genuinely offering her a tour or subtly chastising her for eavesdropping.

“Oh. No,” she said, “it’s okay. Sorry. I was just on my way back from the restrooms and took a peek.”

Smiling, he held out his hand. “David Morris.”

Jess shook it tentatively. “Jessica.”

“We haven’t had clients in the offices for a while. It’s nice to see a fresh face.” As he said this, his eyes did a quick sweep down her body and back up. “You’re doing the DNADuo?”

She resisted the urge to cross her arms over her chest to hide the fact that she’d come to this high-end dating service looking like a hungover college kid. “I haven’t decided yet. I’m here with my best friend. She’s a romance author and completely lost her mind when Americano—Dr. Peña, sorry—mentioned the business to us this morning.”

David gestured for her to lead them both back to the conference room. “Well, I hope you find the technology compelling.”

Jess forced a polite smile. “I’m sure we will.”

David stopped at the threshold to the conference room. “It was nice to meet you, Jessica. If you need anything else, please feel free to reach out.”

With another tight smile, Jess pushed down her bubbling uneasiness. “I absolutely will.”

SHE RETURNED TO the conference room feeling roughly ten percent frumpier than she had before. Which was to say, scraping the bottom of the barrel. Fizzy and Lisa were chatting about the benefits and drawbacks of various dating apps, but they straightened like they’d been busted when Jess walked back in. Without either of them having to say it, Jess knew she absolutely looked the part of the friend who had been dragged along to this and would much rather be watching Netflix on her couch.

“Ready to get started?” Lisa asked, swiping through a menu on an iPad. The room dimmed and a massive screen descended from the ceiling with a soft hum.

Fizzy played her role, “Hell yes!” so Jess played hers, too: “Sure, why not.”

Lisa strode to the front of the large room with confidence, like she was speaking to a crowd of fifty instead of two.

“What are your goals,” she began, “as far as romantic relationships go?”

Jess turned expectantly to Fizzy, who had turned expectantly to Jess.

“Okay, well, I guess I’ll take the first shot,” Fizzy said, scoffing at Jess’s blank expression. “I’m thirty-four, and I enjoy dating. A lot. But I suppose I’ll eventually settle down, have some kids. It all depends on the person.”

Lisa nodded, smiling like this was a perfect answer, and then turned to Jess.

“I…” she began, flailing a little. “I assume there’s someone out there for me, but I’m not really in a rush to find him. I’m about to turn thirty. I have a daughter; I don’t have a lot of time.” Shrugging vaguely, she mumbled, “I don’t really know.”

Clearly Lisa was used to people with a bit more drive, but she rolled out her spiel anyway. “Have you ever wondered what a soulmate truly is?” she asked. “Is love a quality you can quantify?”

“Oooh, good question.” Fizzy leaned in. Hook, line, and sinker.

“Here, we believe it is,” Lisa said. “Matchmaking through DNA technology is exactly what we offer here at GeneticAlly, through the DNADuo. GeneticAlly was officially founded six years ago, but the concept of the DNADuo was first conceived in the lab of Dr. David Morris at the Salk Institute back in 2003.” Lisa swiped from the first image—the DNADuo logo—to an aerial view of the Salk, a stark collection of futuristic buildings just up the road. “The idea of genetic matchmaking is not new, but few companies have been able to create anything even a fraction as extensive as what Dr. Morris and his graduate student, River Peña, designed.”

Jess glanced at Fizzy, who looked back at her. If River and his mentor invented all of this, Jess figured she couldn’t give him too much shit for being a terrible pitch man.

Even if she could give him shit for being a bit of an asshole.

Lisa continued: “The reason the DNADuo has been so successful at identifying genuine love matches is that the idea didn’t start with DNA.” She paused dramatically. “It started with people.”

Jess stifled an eye roll as the slide became animated, zooming away from the Salk research buildings and along a street to a collection of computer-generated coeds standing on the patio of a bar, laughing and talking.

“Dr. Peña first asked whether he could find a complementary pattern in the DNA of two people who are attracted to each other.” Lisa’s slide zoomed in on a couple speaking closely, flirtatiously. “That is, are we programmed to find certain people attractive, and can we predict which two people will be attracted to each other before they ever meet?” She grinned. “In a study of over one thousand students from UC San Diego, a series of nearly forty genes were found to be tightly correlated with attraction. Dr. Peña then pointed the lab in the opposite direction to look into lasting happiness. Could he find a genetic profile of people who had been happily married for longer than a decade?”

Lisa swiped the animation forward to show an older computer-generated couple sitting on a couch, cuddling. The view zoomed back to show a neighborhood, and then a city, and then farther until the city map looked like a double-helix strand of DNA. “From a study of over three hundred couples,” Lisa continued, “Dr. Peña found nearly two hundred genes that were linked to emotional compatibility long-term, including the same forty genes associated with attraction, as well as many other previously uncorrelated ones.” She paused, looking at them. “This was only the first generation of the DNADuo.”

Beside Jess, Fizzy was sitting up at full attention, completely plugged in. But Jess was skeptical. What Lisa was describing was essentially a slot machine with two hundred reels. Statistically speaking, landing on the right combination was an absurdly low-probability event. Even if GeneticAlly was just looking for pattern compatibility, with the number of variants of every gene in the human genome, this type of algorithm was so complex as to be nearly impossible to calculate manually. She couldn’t see how they would begin to process the amount of data they were facing.

Lisa seemed to read her mind. “Two hundred is a lot of genes, and the human genome is made up of at least twenty thousand. Of course, not all of these—maybe not even most—are involved in our emotional satisfaction. But Drs. Peña and Morris wanted to find every last one. They didn’t just want to identify compatibility, they wanted to help you find your soulmate. Which is exactly why Dr. Peña collaborated with Caltech to develop a novel deep neural network.”

She let these words sink in as the slide became animated again, diving into the double helix, highlighting base fragments as it whizzed along the length of the DNA strand.

“This project has encompassed personality tests, brain scans, longitudinal studies of relationship success, and—yes—well over one hundred thousand samples run through DNA sequencing and analysis.” She looked each of them dead in the eye. “The investors have put over thirty million dollars into the technology alone. The app developers have invested almost five million. Do I think we have a truly groundbreaking system?” She nodded. “Between us? In all honesty? I do.”

Swiping forward, she lifted her chin to the screen, where a woman stood alone against a stark white backdrop. “Here’s how it works. We’ve developed a kit like many genetic profiling companies, which, very soon, customers will be able to order by mail. We have kits here for purchase, if you’re interested.”

Jess could sense Fizzy itching to pull out her credit card. Lisa picked up a small box on the table; it was white, the simple DNADuo logo printed in rainbow colors. “Once we fully launch, clients will send in their sample for analysis by our DNADuo algorithm, which now combines findings from over thirty-five hundred genes. Once received, analysis takes only about three days for the results to load into your DNADuo app. While you wait, you can enter information about yourself in your profile—the same way that you would on other dating sites. Information about your age, location, profession—whatever you want people to know about you. Once your results are in, we’ll share with you the compatibility scores based on the criteria you’ve chosen.”

Jess swallowed audibly. All of this sounded so… thorough.

The slide now showed two people standing side by side before the same empty backdrop. “Through rigorous analysis, we’ve created scoring bins. That is, we group the scores based on how tightly they correlate to relationship success. If you pull two random people off the street to see whether they’re compatible, you’re looking at a score on average between seven and twenty-four on our DNADuo algorithm. These scores are out of one hundred, so twenty-four isn’t ideal, but it’s not zero, either. We call these scores Base Matches.”

“Are there a lot of those?” Fizzy asked.

“Oh, yes,” Lisa said. “A large majority of random pairings tested against each other are Base Matches. Now”—she swiped forward, and the two people turned toward each other, smiling—“attraction is frequently reported between couples with scores of twenty-five to fifty, but when we follow them long-term, these individuals rarely find lasting emotional compatibility. We call these Silver Matches, and some of the individuals in our beta testing have chosen to explore these relationships.” Lisa shrugged, grinning, clearly breaking from script. “Good sex is good sex, right?”

Fizzy nodded enthusiastically, but Jess only gave a vague shrug. “What’s your threshold for ‘rarely,’ when you say they rarely find lasting compatibility?”

Lisa smiled. “Based on our initial studies, only one Silver Match in every three hundred lasts beyond the two-year threshold we consider long-term. But here’s where it gets fun,” she said, straightening. A new couple appeared on the screen, holding hands as they walked forward together. “Gold Matches are couples with a score of fifty to sixty-five. A third of Gold Matches will find a lasting relationship together. That number shoots up to two-thirds with a score of sixty-six to eighty—what we call a Platinum Match.”

“Wow,” Fizzy whispered, staring at the new couple laughing together over an intimate candlelit dinner. “That’s a huge jump.”

Lisa nodded. “But three out of four couples find long-term love with scores of eighty to ninety,” she said. “And those are the matches we hope to eventually find for everyone in our database.” She swiped ahead to a couple getting married under a broad arch of flowers. “We call them Titanium.”

Admittedly, Jess had to hide her shock over that statistic. It was impressive. She still had about a million questions, though, and gestured to the couple in the wedding scenario; the woman was Asian, the man of Middle Eastern descent. “It seems from your marketing tools that DNADuo doesn’t have an ethnicity bias.”

“Correct. It’s about finding a soulmate based on a set of biological markers. While there are some genetic variants found across different ethnicities, this technology is about DNA-level compatibility, not symmetry. Not to put too technical a point on it, but in many cases, compatibility is stronger when the two individuals have different genetic markers, rather than the same. And keep in mind, the DNADuo can’t take cultural influences into account, so the importance of all of this information has to be weighed by the client personally. Clients can indicate any and all desired criteria in their intake form—cultural background, religion, et cetera. The algorithm discounts any compatibility findings that don’t fall within their prescribed criteria.”

“So if I’m gay?”

“Sure.” Lisa didn’t hesitate. “On your intake form, you can select to see female matches, male matches, nonbinary matches, or all of the above. As a company, we don’t discriminate based on race, cultural identity, gender, sexual orientation, or religion, and the DNADuo doesn’t, either. Only a handful of the compatibility sequence signatures are located on the X or Y chromosomes; certainly not enough to nullify the data set if a particular sexual genotype is excluded.”

Jess leaned back in her chair, admittedly—and unexpectedly—impressed.

“Sorry, one more question,” Fizzy said. “You said to consider the compatibility scores as one to one hundred… Have you ever seen a score higher than ninety?”

Lisa smiled genuinely. “Only three times.”

“And?” Jess’s heart started slamming against her breastbone. Her brain imagined a different slot machine now, one with 3,500 rows, and a single pull that lined up nearly every single cherry.

For the first time since she walked into the room, Lisa let the hypercompetent surfer-executive façade drop. She looked young, and hopeful, and awestruck: “That’s what gives me the most confidence in this company. Yes, three is a low number, but the couples who’ve tested above ninety are the three couples who’ve scored the highest on emotional stability, communication and collaboration, and sexual satisfaction. They’re Diamond Matches. Do we want more of those? Of course. I mean, the DNADuo has been tested on one hundred and forty thousand people and fully validated in nearly twenty thousand couples. That is an enormous study for a start-up of this size, but there are at least five million people on Hinge and an estimated fifty million people on Tinder. Until we can get the whole world of data in our server, we won’t know how many Diamond Matches are really out there.”